Designer Switches of Cell Fate Could Streamline Stem Cell Biology

Researchers at the University of Wisconsin–Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods. The ability to convert cells from one type to another holds great promise for engineering cells and tissues for therapeutic application, and the new Wisconsin …

Holden Wins Prolific Author Award from Biochemistry Journal

With at least 20 articles published in the journal in the last five years, biochemistry professor Hazel Holden was named a selected highly prolific author by the journal Biochemistry. To mark the publication of the one-millionth article in its many journals, the American Chemical Society, which runs Biochemistry, has honored researchers in different categories. The Holden Laboratory studies the structures and …

Gut’s Microbial Community Shown to Influence Host Gene Expression

In our guts, and in the guts of all animals, resides a robust ecosystem of microbes known as the microbiome. Consisting of trillions of organisms — bacteria, fungi and viruses — the microbiome is essential for host health, providing important services ranging from nutrient processing to immune system development and maintenance. Now, in a study …

Two IPiB Faculty Named 2016 AAAS Fellows

Two Integrated Program in Biochemistry (IPiB) faculty members, have been elected 2016 Fellows of the American Association for the Advancement of Science (AAAS). They are two of five faculty from the University of Wisconsin–Madison named a Fellow this year. David Brow of the Department of Biomolecular Chemistry (BMC) has made contributions to the field of RNA biology, particularly in …

IPiB Students Get Involved in Wisconsin Science Festival

Extracting DNA from wheat germ and talking about the science of sugar — just a few ways students in the Integrated Program in Biochemistry (IPiB) embody the Wisconsin Idea by participating in science outreach. Graduate students from IPiB took part in activities at the Wisconsin Science Festival on Oct. 20-23. Graduate students in IPiB — the joint Ph.D. program of the Department of Biochemistry and …

Beyond Genes: Protein Atlas Scores Nitrogen Fixing Duet

Of the many elusive grails of agricultural biotechnology, the ability to confer nitrogen fixation into non-leguminous plants such as cereals ranks near the very top. Doing so is a huge challenge because legumes partner with bacteria called rhizobia in a symbiotic waltz that enables plants to draw sustenance from the air and transcend the need …

Yeast Knockouts Peel Back Secrets of Cell Protein Function

Proteins are the hammers and tongs of life, with fundamental roles in most of what happens in biology. But biologists still don’t know what thousands of proteins do, and how their presence or absence affects the cell. The intellectual black hole extends to mitochondria, the cells’ energy machines, which falter in more than 150 diseases, …

2016 IPiB Retreat Brings Program Together for Research and Collaboration

The 2016 Integrated Program in Biochemistry (IPiB) Retreat brought new students together with current students, faculty, post doctoral scientists, and researchers to connect with each other both personally and about the research taking place in the program. The event was held Friday, Sept. 9 at the Wisconsin Institutes for Discovery and is put together by the program’s Student …