Congratulations to Our Fall 2019 Ph.D. Graduates

Congratulations to the Integrated Program in Biochemistry (IPiB) students who successfully defended their theses this fall. Read a bit about each of these four new graduates and the research that went into receiving their Ph.D. in biochemistry below. Their broad interdisciplinary work covered research from areas like RNA-protein interactions, single-stranded DNA-binding proteins, and computational biochemistry, …

Can ‘Smart Toilets’ be the Next Health Data Wellspring?

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity — the humble toilet — may have potential to outperform them all. That’s the conclusion of a team of metabolism scientists at the University of Wisconsin–Madison and the Morgridge Institute for Research, who are working to put the tremendous …

Peering into a More ‘Human’ Petri Dish

Cell culture media, the cocktail of chemicals and nutrients that keep cells alive and thriving in a dish, have been an essential tool of biology for more than 70 years. Remarkably, the composition of these potions hasn’t fundamentally changed much over that time, primarily because they deliver what scientists need: Cells that stay viable and …

Biochemistry Affiliate Works to Develop New Bioengineering Strategy

Andrew Buller, professor of chemistry at UW-Madison and affiliate of the Department of Biochemistry, is working to develop methods to create new protein building blocks in living systems. This chemical research, recently recognized with a $2.2 million grant from NIH, could make these processes more affordable for and accessible to scientists with expertise in other backgrounds. …

IPiB Thesis Defense Nov 4: Katarzyna Dubiel

The lab of Professor Jim Keck is broadly interested in bacterial genome maintenance, and IPiB student Katarzyna (Kasia) Dubiel focused her Ph.D. research on single-stranded DNA-binding proteins (SSBs), which play a major role in this process. In order for DNA replication and repair to occur, double-stranded DNA must be separated into single strands. Single-stranded DNA …

Audhya Named Associate Dean for Basic Research for SMPH

Integrated Program in Biochemistry (IPiB) faculty member Anjon Audhya has been named the Associate Dean for Basic Research for the University of Wisconsin–Madison School of Medicine and Public Health. Audhya has been a member of the faculty of the Department of Biomolecular Chemistry since 2008. He leads an internationally renowned research program focused on fundamental …

IPiB Thesis Defense Oct. 18: Samantha Anderson

Membrane proteins are notoriously difficult to study. It’s why scientists have turned to computational methods to try to predict their characteristics. For her thesis research, Samantha Anderson of the Senes Lab investigated a specific motif — a short sequence common among membrane proteins — and how it impacts the way membrane proteins interact with each …

IPiB Thesis Defense Oct. 4: Thao Nguyen

One project in the lab of IPiB faculty member Michael R. Sussman investigates a proton pump present in plant and fungal cells. The pump converts the chemical energy of ATP into an electrical and chemical gradient of protons known as a proton motive force as it moves protons to the outside of the cell. This …