Biochemistry

Butcher, Samuel E.

Structural biology of RNA interactions that regulate gene expression

Interactions of the gut microbiome with the host; intestinal metabolism in health and disease

Understanding and engineering microscale molecular and cellular machines

Molecular basis of bioenergetic systems involved in photosynthesis

Studying the structure and dynamics of biological macromolecules using cryo-EM

Dynamics and function of integral membrane proteins, secondary active transport, ion channels

Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches

Structural and biochemical exploration of RNA virus entry and replication

RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

Mechanism of telomere maintenance; Structure-function studies of biological machines by cryo-EM and single-molecule imaging