Mrinalini Hoon
Credentials: Department of Ophthalmology and Visual Sciences
Position title: Associate Professor
Email: mhoon@wisc.edu
Address:
1111 Highland Ave, WIMR-II Rm 9457
- Lab Website
- Lab Website
- Education
- B.Sc., Calcutta University, India; Ph.D., International Max Planck Research School, University of Goettingen, Germany; Postdoctoral, University of Washington, USA
- Research Areas
- Membrane & Cellular Biophysics, Neuroscience, Spectroscopy Microscopy Imaging
Mechanisms regulating retinal circuit organization and maintenance
Research in the Hoon lab employs a multi-faceted toolkit combining murine transgenic approaches with high resolution light and 3D electron microscopy, molecular biology, transcriptomic and electrophysiology techniques. The objective of our lab’s research is to determine the molecular, cellular and activity-dependent mechanisms that regulate the formation, maturation, function and maintenance of neural circuits in the mammalian retina. Our research also aims to reveal how alterations (and breakdown) of circuit assembly mechanisms degrades neural integrity and functional responses in retinal diseases. Understanding the mechanistic basis of retinal circuit dysfunction can enable formulation of novel therapeutic approaches to restore circuit function during retinal degeneration and disease conditions.