Jiaoyang Jiang
Credentials: Pharmaceutical Sciences Division, School of Pharmacy
Position title: Associate Professor
Email: jjiang68@wisc.edu
Phone: (608) 265-6732
Address:
6113 Rennebohm Hall
777 Highland Ave
Madison, WI 53705-2222
- Lab Website
- Lab website
- Education
- B.S., University of Science and Technology of China; Ph.D., Brown University; Postdoc, Harvard Medical School
- Research Areas
- Biophysical Chemistry; Membrane & Cellular Biophysics; Protein Folding Design & Function; Spectroscopy Microscopy Imaging; Structural Biology

Structure, mechanism and function of protein glycosylation in biology and disease
The overarching goal of our research program is to understand the molecular mechanisms and biological functions of protein glycosylation, especially O-GlcNAcylation. This unique modification dynamically regulates a wide variety of physiological and pathological processes. However, the mechanism underlying its dynamic regulation and aberrant function remains largely unknown. The Jiang Research Group has been active in developing innovative tools, determining novel protein structures, and uncovering regulatory pathways to characterize the functions of O-GlcNAc cycling enzymes (OGT and OGA), and design new strategies to control the level of this modification for drug discovery.
Watch a brief introduction of protein O-GlcNAcylation
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