Lloyd M. Smith

Credentials: Department of Chemistry

Position title: Professor

Email: smith@chem.wisc.edu

Website: Smith Group

Phone: (608) 263-2594

Address:
4209A Chemistry
1101 University Ave
Madison, WI 53706-1322

Lab Website
Lab website
Education
A.B., University of California, Berkeley; Ph.D., Stanford University
Research Areas
Biophysical Chemistry, Computational Biology and AI
Lloyd Smith

Development and application of novel bioanalytical tools

Research in the Smith Lab is broadly focused on the development of technologies to enable the observation of proteoforms that are invisible to current techniques. We approach this both from the lab bench and the computer keyboard. We develop innovative lab methods to advance current proteomic analyses, and open new avenues of proteomics research. We also develop cutting-edge software tools for the accurate and efficient analysis of mass spectrometry proteomics data.

Graph to illustrate bioinformatics

Bioinformatics
Concurrent development of software to more quickly, accurately, and deeply characterize the proteome, and improvement of our ability to visualize proteomics data in highly informative ways.

 

Illustration for ProteoformsProteoforms
Identification and localization of PTM’s, single-nucleotide polymorphisms (SNP’s), and splice variants to more thoroughly characterize proteome complexity in biological systems.

 

Illustration for RNA-Protein interactonsRNA-Protein Interactions
Identification and quantification of RNA-interacting proteins to elucidate their roles in biological systems.