Gellman, Samuel H.
Proteins and protein-like molecules: design, synthesis, structure and function
Interdisciplinary PhD in Structural and Computational Biology and Quantitative Biosciences
Proteins and protein-like molecules: design, synthesis, structure and function
Dynamics and function of integral membrane proteins, secondary active transport, ion channels
Lab Website Lab website Project Title Structure and function of enzymes Biography Virtually every living process, whether it is programmed cell death, mitosis, HIV infection, or embryonic development involves proteins. Indeed, the term protein is derived from the Greek word proteois, which means “first.” My laboratory has had a long-standing interest in protein structure and …
Mechanistic studies of eukaryotic RNA processing using chemical, genetic, and biophysical approaches
Structural mechanisms of genome maintenance
Protein allostery, orthogonal transcriptional systems, programmable synthetic bacteriophages
Lab Website Lab website Project Title Biophysical chemistry of proteins, nucleic acids and their interactions Biography We study the self-assembly and function of proteins, nucleic acids and their complexes, using a wide range of biophysical and biochemical methods including fluorescence, circular dichroism, calorimetry, osmometry, and gel electrophoretic separations of 32P-labeled nucleic acids, quantified by phosphoimager …
Lab Website Lab website Project Title Understanding and engineering microbial communities across space and time Biography The Venturelli Lab aims to understand and engineer the spatiotemporal behaviors of microbial communities. We seek to elucidate the molecular and ecological design principles of microbial communities using tools from systems & synthetic biology. Our lab uses microfabrication methods …
Spatially-resolved mapping of post-translational modifications; protein engineering; chemoproteomics
Protein engineering and biocatalysis