Landick, Robert
RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans
Interdisciplinary PhD in Structural and Computational Biology and Quantitative Biosciences
RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans
Protein allostery, orthogonal transcriptional systems, programmable synthetic bacteriophages
Lab Website Lab website Project Title Biophysical chemistry of proteins, nucleic acids and their interactions Biography We study the self-assembly and function of proteins, nucleic acids and their complexes, using a wide range of biophysical and biochemical methods including fluorescence, circular dichroism, calorimetry, osmometry, and gel electrophoretic separations of 32P-labeled nucleic acids, quantified by phosphoimager …
Lab Website Lab website Project Title Protein engineering, computational biology, high-throughput technology Biography Proteins are amazingly diverse molecules that are capable of performing complex chemical and biological functions. Such versatility presents tremendous opportunities for solving challenging human problems that range from medicine and agriculture to environmental protection and industrial chemistry. However, despite this great potential, …
3D structure of viruses, bacteria, and mammalian cells by cryo-electron microscopy
Understanding and engineering microscale molecular and cellular machines
Biochemical and computational studies of membrane protein interactions